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Interferon, preclinical basis for clinical trials with fibroblast interferon in .
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Interferon, preclinical basis for clinical trials
官方公共微信小木虫 --- 600万学术达人喜爱的学术科研平台
&&查看话题
请教SCIE影响因子
朋友介绍想投International
of Clinical and Experimental Medicine (IJCEM)，朋友告知该杂志是SCIE收入的，但是查不到影响因子（该杂志主页上写的是1.97，非官方数据），我在http://scie-thomsonreuters.org/查不到该杂志，在http://ip-/mjl/能查到SCIE收入，请大侠帮忙并且解释下1：该杂志是否为SCIE收录 2：IF是多少 3：既然是SCIE为什么没有官方IF ，感谢！！
哦，是这样，受教了~
我看清楚了啊，写的是非官方数据啊
不是SCI-E？有证据吗
同样适用SCIE？那这个杂志是SCIE收录吗？
是SCIE收录。
是SCI-E，看一下4L的解释，说明了为什么没有影响因子~
大哥，你搜索的数据库是“Master Journal List”，:sweat:你要把DataBase切换到“Science Citation Index Expanded”才是搜索的SCI-E的期刊好不好。可以肯定的说这个期刊不是SCIE收录的期刊，SCI-E的数据库中查不到。。。
你点击一下“Coverage”就能看到这个期刊的收录情况了，请仔细看一下。
北京学而思教育科技有限公司 地址：北京市海淀区北三环甲18号中鼎大厦A座1层102室 电话：010-您所在位置： &
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Cognitive Reserve in Granulin-Related Frontotemporal Dementia from Preclinical to Clinical Stages.doc 8页
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Cognitive Reserve in Granulin-Related Frontotemporal Dementia from Preclinical to Clinical Stages
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CognitiveReserveinGranulin-RelatedFrontotemporalDementia:fromPreclinicaltoClinicalStagesEnricoPremiAngeloBianchettiBarbaraBorroni1,StefanoGazzina1,MarcoBozzali2,SilvanaArchetti3,AntonellaAlberici,MaraCercignani,145,RobertoGasparotti6,MarinellaTurla,CarloCaltagirone78,AlessandroPadovani,11*1CentreforNeurodegenerativeDisorders,UniversityofBrescia,Brescia,Italy,2NeuroimagingLaboratory,SantaLuciaFoundationIRCCS,Rome,Italy,3IIILaboratoryofAnalysis,BresciaHospital,Brescia,Italy,4BrightonandSussexMedicalSchool,ClinicalImagingCentre,UniversityofSussex,Brighton,UnitedKingdom,5GeriatricResearchGroup,Brescia,Italy,6NeuroradiologyUnit,UniversityofBrescia,Brescia,Italy,7NeurologyUnit,ValleCamonicaHospital,Brescia,Italy,8DepartmentofNeuroscience,UniversityofRome“TorVergata”,Rome,ItalyAbstractObjective:Consistentwiththecognitivereservehypothesis,highereducationandoccupationattainmentsmayhelppersonswithneurodegenerativedementiastobetterwithstandneuropathologybeforedevelopingcognitiveimpairment.Wetestedherethecognitivereservehypothesisinpatientswithfrontotemporaldementia(FTD),withorwithoutpathogeneticgranulinmutations(GRN+andGRN-),andinpresymptomaticGRNmutationcarriers(aGRN+).Methods:EducationandoccupationattainmentswereassessedandcombinedtodefineReserveIndex(RI)in32FTDpatients,i.e.12GRN+and20GRN-,andin17aGRN+.ChangesinfunctionalconnectivitywereestimatedbyrestingstatefMRI,focusingonthesaliencenetwork(SN),executivenetwork(EN)andbilateralfrontoparietalnetworks(FPNs).CognitivestatuswasmeasuredbyFTD-modifiedClinicalDementiaRatingScale.Results:InFTDpatientshigherlevelofpremorbidcognitivereservewasassociatedwithreducedconnectivitywithintheSNandtheEN.ENwasmoreinvolvedinFTDpatientswithoutGRNmutations,whileSNwasmoreaffectedinGRNpathology.InaGRN+,cognitivereservewasassociatedwithreducedSN.Conclusions:ThisstudysuggeststhatcognitivereservemodulatesfunctionalconnectivityinpatientswithFTD,eveninmonogenicdisease.InGRNinheritedFTD,cognitivereservemechanismsoperateeveninpresymptomatictoclinicalstage
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We have completed the validation of the SEND Suite to produce SEND data for studies conducted using our global data capture system.
Our global network of facilities extends throughout Europe, Canada and the United States.
When needed, program managers can provide personal attention and multi-study oversight from the early planning stages through the final reports.
Our unique range of products and related services will effectively support your vaccine program.
SOT 2017 Recap
Visit our Society of Toxicology 2017 recap site to learn more about our presence there and to download all our scientific posters and exhibitor session replays.
Our laboratory services are available to support animal models, discovery, preclinical studies and/or clinical trials.
Over 100,000 square feet of dedicated archival space protected by several layers of security.
Comprehensive pathology-based services in the fields of metabolic bone disease and orthopedics.
We began the validation of the SEND Suite to produce SEND data for all studies conducted using our global data capture system in Jan 2013.
Extensive resources dedicated to pathology support
Our multidisciplinary expertise, state-of-the-art technology and depth of experience with large and small molecules and devices enables us to offer a wide array of integrated anatomic and clinical pathology services.
Our immunology group can evaluate samples for immunogenicity, molecular biology, biomarkers,&immuno- toxicology and immunomodulation.
We offer a comprehensive range of biomarker services in key therapeutic areas from early discovery stages to clinical support.
Our in vitro services provide support in metabolic, toxicokinetic and bioanalytical investigations with both qualitative and quantitative data.
Charles River can develop, validate and apply quantitative bioanalytical methods for the determination of pharmaceutical compounds ranging from small molecules to large proteins.
Laboratory scientists at Charles River utilize fully validated, networked data management systems at all locations. We have the capabilities and capacity to produce rapid and reliable quality data for the pharmaceutical, biotechnology, medical device, chemical and consumer product industries.&
Our field trial operators can conduct studies using the full range of crops, soil types and weather conditions found in Europe.
We perform general toxicology safety evaluation studies for the pharmaceutical, biopharmaceutical, veterinary, chemical, agrochemical and consumer product industries.
We offers physicochemical testing, characterization, analytical chemistry and stability testing in support of product registration for agrochemicals worldwide.
We performs ADME, pharmacokinetic, bioequivalence, residue depletion and target animal safety studies in compliance with EU, VICH, US and Japanese regulations.
Services to Meet REACH Requirements
Charles River has supported the chemical industry for over 40 years. Drawing on our REACH compliance experience, we offer a full range of services to meet the requirements of REACH.
This interactive tool provides you with an estimated timeline to help you better plan your IND program.
Contact us directly using this concise form for your IND program.
Our program managers, regulatory advisers and scientific experts are uniquely qualified to navigate your unique journey, every step of the way.
By being a part of the CDISC SEND team, we were profoundly involved with the development of the CDISC SEND Implementation Guide (SENDIG) Version 3.0.
Evolving with your needs and expectations
With our years of experience, unique range of services, best-in-class expertise and our ongoing efforts to improve upon our internal processes, we are pleased to offer a highly cost-effective IND program for our clients.
Toxicology
We have completed the validation of the SEND Suite to produce SEND data for studies conducted using our global data capture system.
Our global network of facilities extends throughout Europe, Canada and the United States.
When needed, program managers can provide personal attention and multi-study oversight from the early planning stages through the final reports.
Our unique range of products and related services will effectively support your vaccine program.
SOT 2017 Recap
Visit our Society of Toxicology 2017 recap site to learn more about our presence there and to download all our scientific posters and exhibitor session replays.
Our laboratory services are available to support animal models, discovery, preclinical studies and/or clinical trials.
Over 100,000 square feet of dedicated archival space protected by several layers of security.
Comprehensive pathology-based services in the fields of metabolic bone disease and orthopedics.
We began the validation of the SEND Suite to produce SEND data for all studies conducted using our global data capture system in Jan 2013.
Extensive resources dedicated to pathology support
Our multidisciplinary expertise, state-of-the-art technology and depth of experience with large and small molecules and devices enables us to offer a wide array of integrated anatomic and clinical pathology services.
Lab Sciences
Our immunology group can evaluate samples for immunogenicity, molecular biology, biomarkers,&immuno- toxicology and immunomodulation.
We offer a comprehensive range of biomarker services in key therapeutic areas from early discovery stages to clinical support.
Our in vitro services provide support in metabolic, toxicokinetic and bioanalytical investigations with both qualitative and quantitative data.
Charles River can develop, validate and apply quantitative bioanalytical methods for the determination of pharmaceutical compounds ranging from small molecules to large proteins.
Laboratory scientists at Charles River utilize fully validated, networked data management systems at all locations. We have the capabilities and capacity to produce rapid and reliable quality data for the pharmaceutical, biotechnology, medical device, chemical and consumer product industries.&
Chemicals, Agro & Vet
Our field trial operators can conduct studies using the full range of crops, soil types and weather conditions found in Europe.
We perform general toxicology safety evaluation studies for the pharmaceutical, biopharmaceutical, veterinary, chemical, agrochemical and consumer product industries.
We offers physicochemical testing, characterization, analytical chemistry and stability testing in support of product registration for agrochemicals worldwide.
We performs ADME, pharmacokinetic, bioequivalence, residue depletion and target animal safety studies in compliance with EU, VICH, US and Japanese regulations.
Services to Meet REACH Requirements
Charles River has supported the chemical industry for over 40 years. Drawing on our REACH compliance experience, we offer a full range of services to meet the requirements of REACH.
Investigational New Drug
This interactive tool provides you with an estimated timeline to help you better plan your IND program.
Contact us directly using this concise form for your IND program.
Our program managers, regulatory advisers and scientific experts are uniquely qualified to navigate your unique journey, every step of the way.
By being a part of the CDISC SEND team, we were profoundly involved with the development of the CDISC SEND Implementation Guide (SENDIG) Version 3.0.
Evolving with your needs and expectations
With our years of experience, unique range of services, best-in-class expertise and our ongoing efforts to improve upon our internal processes, we are pleased to offer a highly cost-effective IND program for our clients.}